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Faculty and Staff

The faculty Director of the CBT program is Professor David Fruman.

Fruman Nov 2014

The co-Director is Professor Aimee Edinger.

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The primary administrator for the program is Ms. Nita Driscoll (nrdrisco@uci.edu) assisted by Krystina Jarema (kjarema@uci.edu).

Below is a list of Training Faculty in the CBT program, with brief summaries of research interests and links to their lab homepage or faculty profile.

Bogi Andersen

Transcriptional regulation in the developmental biology of epidermis and mammary gland

Bruce Blumberg

Gene regulation by nuclear hormone receptors in vertebrate development and adult physiology

Daniela Bota

The mechanisms of chemotherapy-induced cognitive damage, and differential mechanisms governing glioma stem cell versus neural stem cell differentiation

Xing Dai

Skin and mammary stem cells, Wnt signaling, chromatin, transcription

Michael Demetriou

Tumor immunology, glycobiology, T cell regulation

Aimee Edinger

Cancer bioenergetics, growth factor- and nutrient-dependent signaling, autophagy, intracellular trafficking

David Fruman

Targeting the PI3K/AKT/mTOR pathway in leukemia and lymphoma cells; Targeting the BCL2 pathway

Anand Ganesan

Identify the key molecular regulators of melanin production, melanoma cell survival, and melanoma chemoresistance in human cells

Gultekin Gulsen

Functional onco-imaging

Klemens Hertel

Regulation of gene expression by alternative splicing

Christopher Hughes

Molecular biology of developmental and tumor angiogenesis

Peter Kaiser

Cell cycle control; regulation of proteins by ubiquitination

Mei Kong

Stress adaptation in cancer cells

Young Jik Kwon

Cancer-targeted therapeutics, Engineered viral vectors for gene therapy, Cancer Vaccine

Arthur Lander

Mechanisms of growth factor action; extracellular matrix; developmental neurobiology; systems biology

Charles Limoli

Oxidative stress, Neurogenesis, Stem cells, Transplantation, Chemobrain, Irradiation, Cognitive dysfunction

Michael McClelland

Evolution of Salmonella pathogenesis; bacterial therapy for cancer; cancer genomics and prognostics.

Dan Mercola

Translational research in prostatic cancer

Edward Nelson

Tumor immunology, dendritic cell biology, and anti-tumor immunotherapeutics

Max Plikus

Stem cells and stem cell niche, Regeneration of tissues and organs, Biological pattern formation, Self-organization, Skin and hair follicles, Adipose tissue, WNT and BMP signaling pathways

Tom Poulos

Protein engineering and crystallography on heme containing enzymes and related redox proteins, including nitric oxide synthase, cytochrome P450 and peroxidases

Jennifer Prescher

Probing biological systems with chemical tools and noninvasive imaging

Feng Qiao

Telomeres & telomerase and their roles in cancer and stem cell diseases; Structural, biochemical and molecular genetic analyses of nucleoprotein assemblies

Olga Razorenova

Internal (oncogenes/tumor suppressor genes) and external (tumor microenvironment)
factors regulating tumor progression and metastasis

Paolo Sassone-Corsi

Mechanisms of gene expression and epigenetics

Robert Spitale

RNA Biology and Structure

Lydia Su

Functional onco-imaging

Christine Suetterlin

Centrosome regulation, cilia formation and length control, host-pathogen interaction

Rick Van Etten

Tyrosine kinases and in vivo models of leukemogenesis

Marian Waterman

Wnt signaling and LEF-1 gene expression in lymphocytes and cancer

Greg Weiss

Using molecular evolution in a test tube (phage display) to explore the chemistry and biology of cells

Xiaolin Zi

Natural products, molecular targets, cancer prevention and treatment

Junior Preceptors* in the program are:

Claudia Benavente

Understanding epigenetic deregulation in pediatric cancer tumorigenesis

Alex Boiko

Isolation and Characterization of Tumor Initiating Cells from melanoma patients

Angela Fleischman

Myeloproliferative neoplasm

Kai Kessenbrock

Microenvironmental Control of Stem Cells and Cancer

Devon Lawson

Mechanisms of Cancer Metastasis

Selma Masri

Epigenetic control, circadian biology and metabolism

* Junior Preceptors can serve as co-mentors